MDMA also known as ecstasy is a drug commonly abused by all age groups. The discovery of the drug meant to bring down appetite, reduce hunger; however, this drug not used for the intended purpose because of its nature of producing hallucinogenic effects. Continue reading
Dolophine or methadone is a synthetic opioid with chemical dissimilarity with morphine but pharmacologically similar to that. It has analgesic, respiratory depressant, antitussive, constipating and biliary actions similar to that of morphine. It binds to plasma proteins up to 90%, demethylated and cyclized in the liver and excreted in urine. This forms the basis of dolophine urine testing. Though the abuse potential for methadone lower than that of morphine but cumulates in the tissues. Tolerance to the drug develops more slowly and the withdrawal syndrome arises gradually with less severity.
The mode of intake of methadone is either oral or intravenous. The detection period is from 6 to 12 days. The primary use of dolophine is for the treatment for heroin addiction. So any amount of methadone or dolophine in urine or in the body means that the person is under treatment for heroin addiction. This provides an important clue for the drug abuse. Dolophine drug test can be done using a single panel drug detection screen card. It can be used for both homes and offices. This is a simple dip and read test method.
Drug test for Dolophine can also be done along with other drug tests using multi panel test cards. But the cut off concentration for the detection fro methadone is 300 ng/ ml. though this test is a multi panel test, yet it takes only 5 minutes for the detection. The technique used is the lateral flow chromatography immunoassay. This is designed for professional use and has got the clearance from FDA. Other combinations of drugs that can be tested along with methadone are cocaine, amphetamines, methamphetamines, marijuana, opiate, phencyclidine, barbiturates, benzodiazepines and ecstasy.
Before testing for dolophine you must be familiar with the testing procedures. It is advisable that if you are testing your employees, then you must have a clear medical history of theirs. The reason is that methadone has a lot of therapeutic effects other than having its adverse effects which makes eliciting such a history essential. For instance dolophine is mainly used as substitution therapy of opiod dependence. So when you detect dolophine in the system of your employee, then you have to rule out the possibility of rehabilitation therapy.
Drug test dolophine if tests positive using the home based drug testing kits, then you have to go for the confirmatory tests that are done in the FDA authorized laboratories using higher sensitivity tests like mass spectrometry and gas chromatography.