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Add to cart           This three panel Integrated E-Z Split Key drug test cup tests for combination of Cocaine, Methamphetamine and Marijuana (THC). Our Cocaine/Methamphetamine/ Marijuana(THC) drugs tests are: FDA Approved Tests A simple to administer dip-and-read test designed to detect a specific drug(s) in urine Results are ready in just a few minutes 95% to 98% accurate Set to the SAMSHA Cut-off levels Click here for Test Directions. Click Here for Package Insert Discounts Quantity (no.) Price Discounted Price 1-24 $7.70 $6.45 each 25-49 $7.50 $5.95each 50-99 $7.30 $5.65 each 100-100+ $7.10 $5.45 each The One Step Drug Screen Test Cup is a lateral flow chromatographic immunoassay for the qualitative detection of multiple drugs such as Cocaine, Methamphetamine and Marijuana (THC) drug metabolites in urine at the following cut-off concentrations: Test Calibrator Cut off Cocaine (COC) Benzoylecgonine 300 ng/mL Methamphetamine (mAMP) D-Methamphetamine 1,000 ng/mL Marijuana (THC) 11-nor-∆9-THC-9COOH   50 ng/mL About Cocaine Cocaine is a potent central nervous system (CNS) stimulant and a local anesthetic. Initially, it brings about extreme energy and restlessness while gradually resulting in tremors, over-sensitivity and spasms. In large amounts, cocaine causes fever, unresponsiveness, difficulty in breathing and unconsciousness. Cocaine is often self-administered by nasal inhalation, intravenous injection and free-base smoking. It is excreted in the urine in a short time primarily as Benzoylecgonine. About Methamphetamine Methamphetamine is an addictive stimulant drug that strongly activates certain systems in the brain. Methamphetamine is closely related chemically to amphetamine, but the central nervous system effects of Methamphetamine are greater. Methamphetamine is made in illegal laboratories and has a high potential for abuse and dependence. The drug can be taken orally, injected, or inhaled. Acute higher doses lead to enhanced stimulation of the central nervous system and induce euphoria, alertness, reduced appetite, and a sense of increased energy and power. Cardiovascular responses to Methamphetamine include increased blood pressure and cardiac arrhythmias. More acute responses produce anxiety, paranoia, hallucinations, psychotic behavior, and eventually, depression and exhaustion. The effects of Methamphetamine generally last 2-4 hours and the drug has a half-life of 9-24 hours in the body. Methamphetamine is excreted in the urine as amphetamine and oxidized and delaminated derivatives. However, 10-20% of Methamphetamine is excreted unchanged. Thus, the presence of the parent compound in the urine indicates Methamphetamine use. Methamphetamine is generally detectable in the urine for 3-5 days, depending on urine pH level. The One Step Drug Screen Test Card yields a positive result when the Methamphetamine in urine exceeds 1,000 ng/mL. About Marijuana (THC)  THC (∆9--tetrahydrocannabinol) is the primary active ingredient in cannabis (marijuana). When smoked or orally administered, THC produces euphoric effects. Users have impaired short term memory and slow learning. They may also experience transient episodes of confusion and anxiety. Long-term, relatively heavy use may be associated with behavioral disorders. The peak effect of marijuana administered by smoking occurs in 20-30 minutes and the duration is 90-120 minutes after one cigarette. Elevated levels of urinary metabolites are found within hours of exposure and remain detectable for 3-10 days after smoking.  Analitical Specificity A drug-free urine pool was spiked with drugs at concentrations listed. The results are summarized below. Compound   Concentration (ng/ml) COCAINE                                Benzoylecgonine   300 Cocaine HCl 780 Cocaethylene 12,500 Ecgonine HCl 32,000   METHAMPHETAMINE   ρ-Hydroxymethamphetamine 30,000 L-Methamphetamine    8,000 (±)-3,4-Methylenedioxymethamphetamine   2,000   MARIJUANA (THC)   11-nor-∆9 -THC-9 COOH  50 Cannabinol          20,000 11-nor-∆8-THC-9 COOH 30 ∆8 –THC  15,000 ∆9 -THC 15,000 A configuration of the One Step -Drug Screen Test Card consists of combination of Cocaine, Methamphetamine, Marijuana (THC) drug analytes. This assay provides only a preliminary analytical test result. A more specific alternate chemical method must be used in order to obtain a confirmed analytical result. Gas chromatography/mass spectrometry (GC/MS) is the preferred confirmatory method. Clinical consideration and professional judgment should be applied to the drug of abuse test result, particularly when preliminary positive results are indicated. For more information, click here.